Liquid-Liquid Separators and Back Pressure Regulators

My group at NUS is focusing on development of flow systems to provide new chemical transformations and technologies with relevance to contemporary problems. Back-pressure regulator (BPR) is a key component in a flow system to control the pressure. We had experience with various types of BPRs and I have been impressed with the Zaiput BPR. It is one of the most accurate and reliable BPR we had ever used, with excellent chemical compatibility and easy manipulation. The Zaiput BPR contributes to constant gas/liquid slug flow whereas the spring-type BPR often gave un-even slugs because of the pressure fluctuant. More importantly, the robustness to the presence of solids in continuous-flow makes the Zaiput BPR our daily choice while most of other BPRs will fail with logging. I had used the Zaiput Separator during my postdoc study at Jamison lab. The separators is quite robust. This modular capability of in-line separation has opened a greater level of process integration, especially aiming to future multistep automatic flow synthesis.